We have been taking a look at several wireframe/prototyping approaches for clients seeking to conceptualize a Web site layout prior to site design. Many of these can be handled using the features of Microsoft Word or Photoshop/Illustrator, but I recently stumbled upon a solution that seems to fit the mark: Balsamiq Mockups. This tool seems to be a great fit for developing wireframes on the fly. It’s always nice to find a tool built for a specific purpose (as opposed to adapting a tool for an alternative purpose). It seems to have everything one might need for not only developing a wireframe, but working in real-time with a client to try different concepts.